Peptide Database

Peptide NameAntimicrobial peptide HsAp3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC364H628N110O106S6

DescriptionStandard

        MSRRLILTLVLVTMLVKTMAGMESKWVETTDEIKKRSGTPEKERESGRLLGVVKRYIVCVRNPCPGRRAISEQT
    

Molecular Weight8433.94 Da

Isoelectric Point (pI)10.13

Net Charge (pH 7.0)6.49

Net Charge (pH 7.4) 6.23

Charge Density (pH 7.0) 0.0878

GRAVY Index-0.30

Hydrophobic Moment 0.68

Boman Index-0.15

Instability Index62.58

Aliphatic Index 92.03

Aromaticity 0.0270

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3537.83

LogP -34.76

H-bond Donors 131.0

H-bond Acceptors 119.0

Rotatable Bonds 292.0

Heavy Atoms 586.0

Ring Count 6.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166853 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus spinifer [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram-negative and Gram-positive bacteria