Peptide Database

Peptide NamePYY(3-34) [Peptide YY]

Function Ontology

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC179H273N49O55

DescriptionStandard

        YPIKPEAPGEDASPEELNRYYASLRHYLNLVTRQ
    

Molecular Weight3991.38 Da

Isoelectric Point (pI)5.59

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.41

Charge Density (pH 7.0) -0.0337

GRAVY Index-0.99

Hydrophobic Moment 0.67

Boman Index-0.17

Instability Index86.26

Aliphatic Index 74.71

Aromaticity 0.1176

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1686.24

LogP -15.01

H-bond Donors 57.0

H-bond Acceptors 55.0

Rotatable Bonds 124.0

Heavy Atoms 283.0

Ring Count 9.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109967 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antihyperglycemic Metabolic regulation

Activity0.0039 μM

MethodEC50

Half-LifeFemale pigs blood, in vivo; 216 s