Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length211 amino acids

Chemical FormulaC1082H1688N254O303S8

DescriptionStandard

        YSKRLVLYHVAVYLLVLATVDKYAEIEYSMVTPPSISNFLIELTLLVLMYLQGEFYNIGQHQEPPFSVPPFSLPPQTSSMLYIGLSSFMANSAGFVYNRAGALSLYITDDMVPSSSPIRLNTKTFGAFIPEVSPSLPVASMNLLITNDATGTLTAYAILPNTTLEPLFILNMVEYLQQGFPLPAIGRMNLINSKLQVQKVRLVASLYSFIT
    

Molecular Weight23359.02 Da

Isoelectric Point (pI)5.62

Net Charge (pH 7.0)-2.06

Net Charge (pH 7.4) -2.40

Charge Density (pH 7.0) -0.0097

GRAVY Index0.42

Hydrophobic Moment 0.56

Boman Index0.26

Instability Index53.69

Aliphatic Index 111.80

Aromaticity 0.1137

Extinction Coeff. Reduced 19370.00

Extinction Coeff. Oxidized 19370.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380492 VERIFIED: NO

Provenance & Taxonomy

OrganismParamormyrops kingsleyae [Bacterium]

FamilyBPI

Tax ID1676925

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence