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MYP_014504
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Basic Information
rtCATH2(1-40)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
40 amino acids
C175H296N68O50S
Standard
Sequence
KIRTRRGKDSGGPKMGRKNSKGGWRGRPGSGSRPGFGSGI
Physicochemical Analysis
4184.71 Da
12.00
10.76
10.55
0.2689
-1.49
0.59
-0.41
48.00
19.50
0.0500
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1952.81
-29.61
73.0
62.0
145.0
294.0
6.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0348939 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
RTG-2 cells
Cell viability assay
PMID27818338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27818338/
RECORD: Rec_0355997 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
salmonicida (ATCC 33658)
8-4 μM
MIC
PMID27818338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27818338/
RECORD: Rec_0375779 VERIFIED: YES
Provenance & Taxonomy
Oncorhynchus mykiss [Animal]
Cathelicidin
8022
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
L. garvieae ATCC 49156
16-8 μM
MIC
PMID27818338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27818338/
RECORD: Rec_0409073 VERIFIED: YES
Provenance & Taxonomy
Oncorhynchus mykiss [Animal]
Cathelicidin
8022
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
A. hydrophila ATCC 7966
32 μM
MIC
PMID27818338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27818338/
RECORD: Rec_0427105 VERIFIED: YES
Provenance & Taxonomy
Oncorhynchus mykiss [Animal]
Cathelicidin
8022
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Non-Hemolytic against Human RBCs
Hemolysis
PMID27818338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27818338/
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