Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC794H1201N177O240S8

DescriptionStandard

        QGIVYTPGNYTGSPYVAAPFIIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPMVSLEQDSFTVEIQGSMEVFAVLPDSTTQLLFTMNIAANTSIALNIFDQKLVGSLCLNR
    

Molecular Weight17322.59 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-10.24

Net Charge (pH 7.4) -10.51

Charge Density (pH 7.0) -0.0652

GRAVY Index0.36

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index43.39

Aliphatic Index 91.34

Aromaticity 0.1401

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6598.43

LogP -58.21

H-bond Donors 225.0

H-bond Acceptors 238.0

Rotatable Bonds 548.0

Heavy Atoms 1219.0

Ring Count 31.0

Amide Bonds 170.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335987 VERIFIED: NO

Provenance & Taxonomy

OrganismHimantopus himantopus (Black-winged stilt) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria