Peptide Database

Peptide NamePeptidoglycan recognition protein 1 (Peptidoglycan recognition protein short) (PGRP-S)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length193 amino acids

Chemical FormulaC944H1475N285O265S10

DescriptionStandard

        MTRHCVLLVWALLALLSLGAAREDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA
    

Molecular Weight21377.21 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)6.06

Net Charge (pH 7.4) 5.36

Charge Density (pH 7.0) 0.0314

GRAVY Index-0.19

Hydrophobic Moment 0.80

Boman Index0.02

Instability Index42.88

Aliphatic Index 87.46

Aromaticity 0.0829

Extinction Coeff. Reduced 44920.00

Extinction Coeff. Oxidized 45295.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8764.63

LogP -103.34

H-bond Donors 315.0

H-bond Acceptors 288.0

Rotatable Bonds 678.0

Heavy Atoms 1504.0

Ring Count 41.0

Amide Bonds 208.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053564 VERIFIED: YES

Provenance & Taxonomy

OrganismCamelus dromedarius [Animal]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Tax ID9838

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-positive Chemotactic Cytotoxic Non-hemolytic

TargetGram-positive bacteria