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MYP_014426
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Basic Information
C6 11 F13
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
20 amino acids
C111H162N22O25S2
Standard
Sequence
LEAIPCSIPPCVFFNKPFVF
Physicochemical Analysis
2268.74 Da
5.99
-0.26
-0.49
-0.0129
1.05
0.31
0.46
22.64
92.50
0.2000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
707.70
-1.20
23.0
27.0
63.0
160.0
8.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0269909 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-11
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1
0.93±0.05 μM
IC50
PaperDiscovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide PMID17448989 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17448989/
RECORD: Rec_0327566 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 15.0%, E 0.0%, T 40.0%, C 45.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
RECORD: Rec_0359635 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-11
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperDiscovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide PMID17448989 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17448989/
RECORD: Rec_0423624 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
6-11
Bio-Activity Profile
Antimicrobial Antiviral
PaperDiscovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide PMID17448989 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17448989/
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