Peptide Database

Peptide NamePeptide BmKn2 (Kn2) (Non-disulfide-bridged peptide 4.4) (NDBP-4.4) (Non-disulfide-bridged peptide 5.4) (NDBP-5.4)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antiviral

Antiviral ▸ Anti-HIV

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC366H589N87O101S5

DescriptionStandard

        MKSQTFFLLFLVVLLLAISQSEAFIGAIANLLSKIFGKRSMRDMDTMKYLYDPSLSAADLKTLQKLMENY
    

Molecular Weight7984.44 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0214

GRAVY Index0.36

Hydrophobic Moment 0.64

Boman Index0.16

Instability Index37.38

Aliphatic Index 111.57

Aromaticity 0.1143

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3044.59

LogP -20.78

H-bond Donors 106.0

H-bond Acceptors 108.0

Rotatable Bonds 274.0

Heavy Atoms 559.0

Ring Count 9.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130578 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetPseudomonas aeruginosa (Gram-negative)

RECORD: Rec_0136379 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

RECORD: Rec_0175721 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetBacillus subtilis (Gram-positive)

RECORD: Rec_0278821 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0292729 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Anti-HIV Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)