Peptide Database

Peptide NameB-HR2-scrambled

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC89H150N28O34

DescriptionStandard

        DVREEEQLGERATGLNLNI
    

Molecular Weight2156.31 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-3.23

Net Charge (pH 7.4) -3.44

Charge Density (pH 7.0) -0.1699

GRAVY Index-0.87

Hydrophobic Moment 0.61

Boman Index-0.22

Instability Index68.62

Aliphatic Index 102.63

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1046.92

LogP -11.89

H-bond Donors 35.0

H-bond Acceptors 31.0

Rotatable Bonds 76.0

Heavy Atoms 151.0

Ring Count 0.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0043069 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman alphaherpesvirus 1 [Virus]

FamilyHeptad repeat peptide

Tax ID10298;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsScrambled sequence control

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetHerpes simplex virus 1 (Virus entry); Vero

MethodPlaque assay

PaperAnalysis of synthetic peptides from heptad-repeat domains of herpes simplex virus type 1 glycoproteins H and B. | Galdiero S, Vitiello M, D'Isanto M, Falanga A, Collins C, Raieta K, Pedone C, Browne H, Galdiero M. | J Gen Virol. 2006 | PMID:16603508 PMID16603508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16603508/

RECORD: Rec_0392359 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 15.8%, E 0.0%, T 52.6%, C 31.6% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial