Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC368H594N106O109S12

DescriptionStandard

        MAQFIRSSVSATFLLLVLLAEMGPTTVEGRKCESPSHKFKGMCMNRDNCATVCQTEGYEDGKCEGFRRRCICIKPCF
    

Molecular Weight8632.08 Da

Isoelectric Point (pI)8.48

Net Charge (pH 7.0)2.52

Net Charge (pH 7.4) 2.12

Charge Density (pH 7.0) 0.0327

GRAVY Index-0.12

Hydrophobic Moment 0.51

Boman Index-0.04

Instability Index47.55

Aliphatic Index 60.78

Aromaticity 0.0779

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3472.02

LogP -37.29

H-bond Donors 130.0

H-bond Acceptors 125.0

Rotatable Bonds 290.0

Heavy Atoms 595.0

Ring Count 10.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0147282 VERIFIED: NO

Provenance & Taxonomy

OrganismGossypium raimondii [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence