Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC376H586N98O106S9

DescriptionStandard

        MRIFYYLLHFLCYVTFILPATCTLVDADRCTKRYGRCKRDCLESEKQIDICSSPRKICCTERLYEEDYIF
    

Molecular Weight8463.85 Da

Isoelectric Point (pI)7.50

Net Charge (pH 7.0)0.52

Net Charge (pH 7.4) 0.11

Charge Density (pH 7.0) 0.0074

GRAVY Index-0.11

Hydrophobic Moment 0.81

Boman Index-0.07

Instability Index66.53

Aliphatic Index 83.57

Aromaticity 0.1429

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3319.01

LogP -24.53

H-bond Donors 128.0

H-bond Acceptors 117.0

Rotatable Bonds 278.0

Heavy Atoms 589.0

Ring Count 13.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269923 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence