Peptide Database

Peptide NameDefensin-like protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Plant bioactivity ▸ Plant defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length139 amino acids

Chemical FormulaC646H995N187O209S20

DescriptionStandard

        MIKFFKVFFILALLVFTSVKVNGAQCEEEIGICDENCSSKCEASKNGKGICAKSSLNGIRTCKCLYECNGNVNNNDNDDNNEEHKNPECNMGIGRCGVFCNDDCCNHNCVKRFHDGYGTCIGDIGTPSAYNCVCYYHCH
    

Molecular Weight15366.24 Da

Isoelectric Point (pI)5.67

Net Charge (pH 7.0)-4.22

Net Charge (pH 7.4) -5.00

Charge Density (pH 7.0) -0.0304

GRAVY Index-0.34

Hydrophobic Moment 0.59

Boman Index-0.02

Instability Index25.59

Aliphatic Index 59.57

Aromaticity 0.0863

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6427.33

LogP -78.82

H-bond Donors 232.0

H-bond Acceptors 230.0

Rotatable Bonds 514.0

Heavy Atoms 1062.0

Ring Count 19.0

Amide Bonds 157.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301322 VERIFIED: YES

Provenance & Taxonomy

OrganismGossypium hirsutum [Plant]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Antifungal Non-hemolytic

RECORD: Rec_0357534 VERIFIED: NO

Provenance & Taxonomy

OrganismGossypium barbadense [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Plant defense Non-hemolytic Non-ribosomal