Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC147H219N39O39S2

DescriptionStandard

        AANPHLCGSHLVEALYLVCGERGFFYQPK
    

Molecular Weight3220.68 Da

Isoelectric Point (pI)6.94

Net Charge (pH 7.0)-0.05

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0016

GRAVY Index0.10

Hydrophobic Moment 0.36

Boman Index0.18

Instability Index21.02

Aliphatic Index 84.14

Aromaticity 0.1379

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1227.29

LogP -9.14

H-bond Donors 43.0

H-bond Acceptors 43.0

Rotatable Bonds 99.0

Heavy Atoms 227.0

Ring Count 8.0

Amide Bonds 30.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0107667 VERIFIED: YES

Provenance & Taxonomy

OrganismKatsuwonus pelamis [Animal]

FamilyInsulin

Tax ID8226

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour