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MYP_014327
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Basic Information
MCdef
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Standard
44 amino acids
C205H319N65O64S8
Standard
Sequence
GFGCPNDYSCSNHCRDSIGCRGGYCKYQLICTCYGCKKRRSIQE
Physicochemical Analysis
4974.64 Da
8.71
3.77
3.38
0.0857
-0.69
0.36
-0.20
65.15
35.45
0.1136
5960.00
6460.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2126.50
-27.95
84.0
77.0
164.0
342.0
7.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036971 VERIFIED: YES
Provenance & Taxonomy
Manila clams [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. iniae KCTC 3651, Staphylococcus aureus KCTC 1916
1.25-2.5 μM
MIC
PaperCloning and localization of MCdef, a defensin from Manila clams (Ruditapes philippinarum).
RECORD: Rec_0072593 VERIFIED: YES
Provenance & Taxonomy
Ruditapes philippinarum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Aliivibrio logei KCCM 12281
10-20 μM
MIC
PMID21945146 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21945146/
RECORD: Rec_0098664 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0100373 VERIFIED: YES
Provenance & Taxonomy
Ruditapes philippinarum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus iniae KCTC 3651
1.25-2.5 μM
MIC
PMID21945146 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21945146/
RECORD: Rec_0117790 VERIFIED: YES
Provenance & Taxonomy
Ruditapes philippinarum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus KCTC 1916
1.25-2.5 μM
MIC
PMID21945146 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21945146/
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