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MYP_014302
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Basic Information
cFΦR4-Rho
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FXRRRRQKX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0072472 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Rho, rhodamine B
Φ=L-2-naphthylalanine
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic Cell-penetrating peptide Cellular uptake Endosomal escape
HeLa human cervical cancer cells
Live-cell confocal microscopy / cellular uptake and endosomal escape assay
PMID24896852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24896852/
RECORD: Rec_0157221 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
FITC, fluorescein isothiocyanate
Φ=L-2-naphthylalanine
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID24896852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24896852/
RECORD: Rec_0228378 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Dex, dexamethasone
Φ=L-2-naphthylalanine
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID24896852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24896852/
RECORD: Rec_0298325 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Rho, rhodamine B
Φ=L-2-naphthylalanine
Bio-Activity Profile
Antimicrobial Anticancer
PMID24896852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24896852/
RECORD: Rec_0316468 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Dex, dexamethasone
Φ=L-2-naphthylalanine
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID24896852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24896852/
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