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MYP_014293
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Basic Information
Sema3A(aa363-377) -nLytic
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
32 amino acids
C185H304N48O39
Standard
Sequence
NYQWVPYQGRVPYPRGGLLKLLKKLLKKLLKL
Physicochemical Analysis
3824.69 Da
10.53
7.75
7.53
0.2422
-0.35
0.81
-0.05
0.55
127.81
0.1250
9970.00
9970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1424.72
-4.16
49.0
47.0
128.0
272.0
8.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025218 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Anticancer
PaperPatent US 2011/0319336 A5 Evidence URLhttps://patents.google.com/patent/US20110319336A5/en PatentUS 2011/0319336 A5
RECORD: Rec_0047549 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
Pane- 1
13.1 μM
IC50
PaperSelective anticancer chimeric peptide Evidence URLhttps://patents.google.com/patent/WO2010064207A2/en PatentWO2010064207A2
RECORD: Rec_0057422 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0060090 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
SU.86.86
7.9 μM
IC50
PaperSelective anticancer chimeric peptide Evidence URLhttps://patents.google.com/patent/WO2010064207A2/en PatentWO2010064207A2
RECORD: Rec_0127894 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
CFPAC-I
10.6 μM
IC50
PaperSelective anticancer chimeric peptide Evidence URLhttps://patents.google.com/patent/WO2010064207A2/en PatentWO2010064207A2
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