Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length502 amino acids

Chemical FormulaC2503H3980N634O734S21

DescriptionStandard

        MREMVKICCSLLILSLLSGQLSANPGLKVRITQKGLEYAKEVGLEILKQNMEKERFPDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLQPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNTGPTSISLTSCQTASGDIDIKLNRKTGFLHNFFIKYLKKPIHRSLVTNSCPNIRAGIQLIDEDLRSLNAAMQIDDLAEVDYSLSSLPAVFQPFIDLDLKGVVFPVGNYTDSPFVAASSTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTLAEETCSYFNINTEIFGSIIPEVAKYSVTAYPVMLKLMATEIPLISLQQDSFTVEIQGSMEVVASLPDSTTQSLFTLNIAANSSISLNIFDQKLMGSLCLNRVQFSLAHSNVGSFEVLLLENILSYILQTEVIPSANAKLSKGLPLPNLANVTLTRPHITIVELFFAEIPKSLFAVKHKTQLRKKNAKVVCNCSLTPTYLVPYKM
    

Molecular Weight55371.55 Da

Isoelectric Point (pI)7.07

Net Charge (pH 7.0)0.16

Net Charge (pH 7.4) -0.69

Charge Density (pH 7.0) 0.0003

GRAVY Index0.17

Hydrophobic Moment 0.77

Boman Index0.15

Instability Index38.02

Aliphatic Index 103.13

Aromaticity 0.0876

Extinction Coeff. Reduced 33350.00

Extinction Coeff. Oxidized 33850.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0258985 VERIFIED: NO

Provenance & Taxonomy

OrganismCyanistes caeruleus (Eurasian blue tit) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria