Peptide Database

Peptide NameSLAY-screened peptide P3973

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC55H75N13O16

DescriptionStandard

        FLSNFERFD
    

Molecular Weight1174.26 Da

Isoelectric Point (pI)4.67

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1370

GRAVY Index-0.40

Hydrophobic Moment 0.60

Boman Index-0.06

Instability Index5.90

Aliphatic Index 43.33

Aromaticity 0.3333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 495.94

LogP -3.48

H-bond Donors 17.0

H-bond Acceptors 15.0

Rotatable Bonds 37.0

Heavy Atoms 84.0

Ring Count 3.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269218 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/