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MYP_014267
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Basic Information
IDP-H14-H2-01
Anticancer
Antimicrobial
not Standard
17 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RVKLVNLXFQALRQXVP
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0102288 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
noncanonical residue-containing peptide [Modified]
Hydrocarbon side-chain staple formed from noncanonical olefinic amino acid residues at X positions
Bio-Activity Profile
Antimicrobial Anticancer
H-5B small-cell lung cancer cells
≈2.5 μM
cell proliferation inhibition assay (EC50)
PaperPatent US 2011/0319336 A3 Evidence URLhttps://patents.google.com/patent/US20110319336A3/en PatentUS 2011/0319336 A3
RECORD: Rec_0432062 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
H14 stapled peptide
Structure & Mods
side-chain cyclized peptide [Cyclic]
noncanonical residue-containing peptide [Modified]
Hydrocarbon side-chain staple formed from noncanonical olefinic amino acid residues at X positions
Bio-Activity Profile
Anticancer Antiproliferative
NCI-H82 small-cell lung cancer cells
≈7.5 μM
cell proliferation inhibition assay (EC50)
PaperAnticancer peptides PatentUS11440939B2
RECORD: Rec_0432063 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
H14 stapled peptide
Structure & Mods
side-chain cyclized peptide [Cyclic]
noncanonical residue-containing peptide [Modified]
Hydrocarbon side-chain staple formed from noncanonical olefinic amino acid residues at X positions
Bio-Activity Profile
Anticancer Antiproliferative
NCI-H187 small-cell lung cancer cells
≈7.5 μM
cell proliferation inhibition assay (EC50)
PaperAnticancer peptides PatentUS11440939B2
RECORD: Rec_0432064 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
H14 stapled peptide
Structure & Mods
side-chain cyclized peptide [Cyclic]
noncanonical residue-containing peptide [Modified]
Hydrocarbon side-chain staple formed from noncanonical olefinic amino acid residues at X positions
Bio-Activity Profile
Anticancer Antiproliferative
H-510A small-cell lung cancer cells
≈7.5 μM
cell proliferation inhibition assay (EC50)
PaperAnticancer peptides PatentUS11440939B2