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MYP_014237
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Basic Information
Temporin-TP3
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
17 amino acids
C97H152N18O20
Standard
Sequence
FLPLLFGALSTLLPKIF
Physicochemical Analysis
1890.35 Da
8.75
0.76
0.55
0.0447
1.68
0.42
0.64
22.08
166.47
0.1765
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
577.82
1.37
19.0
21.0
57.0
135.0
5.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0167385 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/E7EKH0/entry
RECORD: Rec_0192248 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
Temporin
110118
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antioxidant
ATCC 10231
>100 μM
MIC
PaperIdentification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0200611 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecium 091299
PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0214783 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
Temporin
110118
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antioxidant
Escherichia coli ATCC 25922
>100 μM
MIC
PaperIdentification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0237657 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Anti-Gram-positive Cytotoxic
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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