Peptide Database

Peptide NameEsculentin-2SN1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC174H276N48O46S2

DescriptionStandard

        GIFSLFKAGAKFFGKNLLKEAGKAGAEHLACKAANQC
    

Molecular Weight3840.48 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.83

Net Charge (pH 7.4) 3.53

Charge Density (pH 7.0) 0.1034

GRAVY Index0.09

Hydrophobic Moment 0.63

Boman Index0.13

Instability Index-2.34

Aliphatic Index 74.32

Aromaticity 0.1081

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1519.82

LogP -14.29

H-bond Donors 53.0

H-bond Acceptors 53.0

Rotatable Bonds 133.0

Heavy Atoms 270.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417125 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana spinulosa [Animal]

FamilyEsculentin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide31-37

Bio-Activity Profile

Function

Antimicrobial

TargetEscherichia coli ATCC 25922

Activity>400 μM

MethodMIC

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