Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC790H1241N229O236S4

DescriptionStandard

        MVEINNQRKAFLDMLAWSEGTDNGHQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNLKLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPESQDAVALQQIKERGALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIEV
    

Molecular Weight17850.96 Da

Isoelectric Point (pI)7.85

Net Charge (pH 7.0)0.86

Net Charge (pH 7.4) 0.38

Charge Density (pH 7.0) 0.0055

GRAVY Index-0.57

Hydrophobic Moment 0.68

Boman Index-0.08

Instability Index26.79

Aliphatic Index 80.95

Aromaticity 0.0886

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7576.11

LogP -75.09

H-bond Donors 264.0

H-bond Acceptors 245.0

Rotatable Bonds 605.0

Heavy Atoms 1259.0

Ring Count 26.0

Amide Bonds 172.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0246327 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage JEP4 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic