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MYP_014178
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Basic Information
RBD-11b
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
6 amino acids
C45H64N10O10
Standard
Sequence
YKYRYL
Physicochemical Analysis
905.05 Da
9.53
1.76
1.55
0.2927
-1.42
0.36
-0.36
-32.42
65.00
0.5000
4470.00
4470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
357.43
0.11
14.0
12.0
27.0
65.0
3.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0064408 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
RBD-derived peptide
694009
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
1400 μM
IC90
PaperA hexapeptide of the receptor-binding domain of SARS corona virus spike protein blocks viral entry into host cells via the human receptor ACE2 PMID22265858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22265858/
RECORD: Rec_0165163 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
RBD-derived peptide
694009
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
700 μM
IC90
PaperA hexapeptide of the receptor-binding domain of SARS corona virus spike protein blocks viral entry into host cells via the human receptor ACE2 PMID22265858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22265858/
RECORD: Rec_0242924 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
Virus-derived peptide
694009;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
SARS coronavirus (Virus entry); Vero E6
RT-PCR
PaperA hexapeptide of the receptor-binding domain of SARS corona virus spike protein blocks viral entry into host cells via the human receptor ACE2. | Struck AW, Axmann M, Pfefferle S, Drosten C, Meyer B. | Antiviral Res. 2012 | PMID:22265858 PMID22265858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22265858/
RECORD: Rec_0254608 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/