Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length436 amino acids

Chemical FormulaC2168H3420N564O629S15

DescriptionStandard

        MSLWCLLLLLALPDPTVSTNPGVKVQITQKALDNGRQIGIAYLEEKLKSVKISNISGSEDVSPIGDVEYRLSGMRITDLGLPQSSLGLVPGTGISLSIGNAFINLHGDWHVTYLGFIQDSGCFDLDISGLTIKATISVGSDETGRPSVSSNDCVARVGDANIDFHEGASWLYNLFTSFIDQALHDSLENQLRYNKMLAMYHLVFVHLLVLATVDKYAEIEYSMVTPPSISNFLIELSLKGEFYNIGQHQEPPFSAPPFSLPPQTSSMLYIGLSSFMANSAGFVYNRARPLSLYITDDMIPSSFPMRLNTRTFGAFVPEISKRFPDMKVKILLKTSTQPKVTFEPNNVILQLIGSFTAYAILPNTTLEPLFTYKVGGAGRHSRHVGDHCFRAKISVSLSKTINQGVSLPGIGRMNLINSKLQVKKVRLLTPLNSFKT
    

Molecular Weight47930.72 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)2.36

Net Charge (pH 7.4) 1.49

Charge Density (pH 7.0) 0.0054

GRAVY Index0.07

Hydrophobic Moment 0.63

Boman Index0.13

Instability Index37.65

Aliphatic Index 99.47

Aromaticity 0.0894

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37610.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304410 VERIFIED: NO

Provenance & Taxonomy

OrganismParamormyrops kingsleyae [Bacterium]

FamilyBPI

Tax ID1676925

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence