Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC399H643N117O120S12

DescriptionStandard

        MKTFSVAVAVAVVLTFICVQQSSALPLTDLQLGEPLRFDSTAAEHEEKLVDSGKCLHTLHRRGEKDCRFCCGCCPNMKGCGHCCTH
    

Molecular Weight9383.87 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.78

Charge Density (pH 7.0) -0.0017

GRAVY Index0.05

Hydrophobic Moment 0.65

Boman Index0.03

Instability Index47.41

Aliphatic Index 75.93

Aromaticity 0.0465

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3762.14

LogP -41.47

H-bond Donors 140.0

H-bond Acceptors 137.0

Rotatable Bonds 310.0

Heavy Atoms 648.0

Ring Count 12.0

Amide Bonds 89.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0035373 VERIFIED: NO

Provenance & Taxonomy

OrganismMola mola [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal