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MYP_014093
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Basic Information
Decoralin [AT3]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
11 amino acids
C66H126N18O12
Standard
Sequence
RLLLLIRKLIL
Physicochemical Analysis
1363.82 Da
12.00
2.76
2.55
0.2508
1.72
0.56
0.23
18.88
283.64
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
504.14
1.27
19.0
15.0
49.0
96.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036645 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HDMEC
160±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0062975 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: 1205Lu
18±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0161983 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0207521 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Jurkat
40±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0210111 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
24±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
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