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MYP_014036
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Basic Information
W8R
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
8 amino acids
C63H90N20O9
Standard
Sequence
WWWLRRIR
Physicochemical Analysis
1271.52 Da
12.00
2.76
2.56
0.3450
-0.99
0.60
-0.34
119.85
97.50
0.3750
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
500.09
0.85
21.0
12.0
37.0
92.0
6.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0110303 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
12.5 μM
MIC
PMID28731688 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28731688/
RECORD: Rec_0120415 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
K-pneumoniae ATCC 13883
>25 μM
MIC
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0129592 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human RBCs
200 μM
Hemolysis
PMID28731688 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28731688/
RECORD: Rec_0158625 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
human RBC: not hemo.lytic
>200 μM
HC50
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0228322 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa PAO1
12.5 μM
MIC
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
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