Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC787H1182N178O241S8

DescriptionStandard

        QGIVYPAGNYSGPPYVAAPFTVPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCNYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPTVSLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIAPNIFDQKLMGSLCLNR
    

Molecular Weight17249.37 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-10.24

Net Charge (pH 7.4) -10.51

Charge Density (pH 7.0) -0.0652

GRAVY Index0.23

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index51.91

Aliphatic Index 82.04

Aromaticity 0.1401

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6623.94

LogP -62.48

H-bond Donors 224.0

H-bond Acceptors 239.0

Rotatable Bonds 540.0

Heavy Atoms 1214.0

Ring Count 33.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008152 VERIFIED: NO

Provenance & Taxonomy

OrganismCochlearius cochlearius [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria