Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC488H787N117O130S9

DescriptionStandard

        MKLFLVLIILQFEVPIDTACPRKCFSNIIGYCWKKCEMGEIYEVACLNGKLCCVNEVKIKKHKKAPESPFSLPQPDGKIDYVILPTTTLLTVQL
    

Molecular Weight10661.76 Da

Isoelectric Point (pI)8.48

Net Charge (pH 7.0)2.52

Net Charge (pH 7.4) 2.12

Charge Density (pH 7.0) 0.0269

GRAVY Index0.24

Hydrophobic Moment 0.48

Boman Index0.15

Instability Index50.04

Aliphatic Index 107.77

Aromaticity 0.0851

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3917.45

LogP -23.75

H-bond Donors 137.0

H-bond Acceptors 143.0

Rotatable Bonds 353.0

Heavy Atoms 744.0

Ring Count 17.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149058 VERIFIED: NO

Provenance & Taxonomy

OrganismMustela putorius furo [Animal]

FamilyDefensin

Tax ID9669

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal