Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length136 amino acids

Chemical FormulaC670H1064N202O192S13

DescriptionStandard

        MLCCAEPSQPQWVSLSLQLIIFSDSGKFSRRKVGMKGGQGCQAGLEFSEPFPSDRGSDKPDQHTYGRRSRPGYSKKFKRSYVVYPNHTMTRTAIHRALICKRMEGHCEAECLTFEVKIGGCRAELTPYCCKTRKKH
    

Molecular Weight15437.70 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)11.86

Net Charge (pH 7.4) 11.22

Charge Density (pH 7.0) 0.0872

GRAVY Index-0.67

Hydrophobic Moment 0.63

Boman Index-0.17

Instability Index49.36

Aliphatic Index 52.35

Aromaticity 0.0882

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6370.48

LogP -69.83

H-bond Donors 235.0

H-bond Acceptors 222.0

Rotatable Bonds 516.0

Heavy Atoms 1077.0

Ring Count 26.0

Amide Bonds 142.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283751 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence