Peptide Database

Peptide Namehepcidin TH2-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC81H132N28O27S6

DescriptionStandard

        QSHLSLCRYCCNCCSNKGC
    

Molecular Weight2122.48 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)1.79

Net Charge (pH 7.4) 1.44

Charge Density (pH 7.0) 0.0940

GRAVY Index-0.19

Hydrophobic Moment 0.47

Boman Index-0.15

Instability Index35.11

Aliphatic Index 41.05

Aromaticity 0.0526

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 913.91

LogP -14.27

H-bond Donors 38.0

H-bond Acceptors 36.0

Rotatable Bonds 69.0

Heavy Atoms 142.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008162 VERIFIED: YES

Provenance & Taxonomy

OrganismPygocentrus nattereri [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)