Peptide Database

Peptide NameCliotide T4

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC600H930N156O172S14

DescriptionStandard

        MASLRIAPLALFFFLAASVMFTVEKTEAGIPCGESCVFIPCITAAIGCSCKSKVCYRNHVIAAEAKTMDDHHLLCQSHEDCITKGTGNFCAPFPDQDIKYGWCFRAESEGFLLKDHLKMSITN
    

Molecular Weight13529.65 Da

Isoelectric Point (pI)6.17

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.0175

GRAVY Index0.22

Hydrophobic Moment 0.45

Boman Index0.15

Instability Index30.38

Aliphatic Index 79.43

Aromaticity 0.0976

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5166.88

LogP -46.71

H-bond Donors 187.0

H-bond Acceptors 189.0

Rotatable Bonds 441.0

Heavy Atoms 942.0

Ring Count 23.0

Amide Bonds 127.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0079278 VERIFIED: NO

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Tax ID43366

Structure & Mods

Configbackbone-cyclized cyclotide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0160549 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Animal]

FamilyCyclotide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Cytolytic Cytotoxic Hemolytic

TargetPseudomonas aeruginosa (Gram-negative)

RECORD: Rec_0169712 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Animal]

FamilyCyclotide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Cytolytic Cytotoxic Hemolytic

TargetK. pneumoniae (Gram-negative)

RECORD: Rec_0406345 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Animal]

FamilyCyclotide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Cytolytic Cytotoxic Hemolytic

TargetEscherichia coli (Gram-negative)