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MYP_013912
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Basic Information
Alyteserin-2a [S7k]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C75H137N19O20
Standard
Sequence
ILGKLLKTAAGLLSNL
Physicochemical Analysis
1625.01 Da
10.00
1.76
1.55
0.1099
1.08
0.50
0.37
5.49
183.12
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
635.41
-4.20
22.0
22.0
57.0
114.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0371614 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii NM8
64 μM
MIC
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0392872 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Drug Delivery Vehicle Cell-penetrating peptide Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0402074 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: A549
35 μM
LC50
PMID22965637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0420039 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
28 μM
Hemolysis
PMID22965637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0421884 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus epidermidis RP62A
4 μM
MIC
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
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