Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC505H806N144O133S10

DescriptionStandard

        MRFWLLTLTVFLILFQMLPVCRGRTSCWIVKGHCRKDCKFGEQVKKPCKNGDYCCIPTKTDFQPHRPIQAPTRNSQTVNSLKRNDFAGLVPVVVMQQE
    

Molecular Weight11343.34 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)8.61

Net Charge (pH 7.4) 8.17

Charge Density (pH 7.0) 0.0879

GRAVY Index-0.23

Hydrophobic Moment 0.67

Boman Index-0.04

Instability Index34.29

Aliphatic Index 76.43

Aromaticity 0.0918

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4475.21

LogP -40.32

H-bond Donors 160.0

H-bond Acceptors 154.0

Rotatable Bonds 372.0

Heavy Atoms 792.0

Ring Count 20.0

Amide Bonds 108.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093371 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence