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MYP_013850
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Basic Information
Angiotensin I-converting enzyme inhibitor II
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C32H50N12O8S
Standard
Sequence
MRWRD
Physicochemical Analysis
762.88 Da
9.35
0.50
0.29
0.1009
-2.30
0.40
-0.90
107.48
0.00
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
356.61
-2.18
14.0
10.0
24.0
53.0
2.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080680 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Antioxidant ACE inhibitory
Angiotensin-converting enzyme
2.1 μM
IC50
RECORD: Rec_0082824 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
ACE inhibitory peptide
3562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Antioxidant ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
PaperPubMed PMID 1290394 | PubMed PMID 2626907 | PubMed PMID 7000000 PMID1290394;2626907;7000000;12903942;62690;77000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1290394/
RECORD: Rec_0122283 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
2.09 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0144352 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
2.1 μM
IC50
PaperIntegration of QSAR modelling and QM/MM analysis to investigate functional food peptides with antihypertensive activity
RECORD: Rec_0152876 VERIFIED: NO
Provenance & Taxonomy
Spinacia oleracea [Plant]
ACE-inhibitory peptide
3562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Antioxidant
Spontaneously hypertensive rat (SHR)
5 mmHg
SBP decrease
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
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