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MYP_013759
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Basic Information
AMP2041 (De novo synthesis)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C92H147N29O19S2
Standard
Sequence
HKCAKIKWRGVHVKYCA
Physicochemical Analysis
2027.46 Da
9.90
4.91
4.57
0.2888
-0.45
0.46
-0.14
6.66
68.82
0.1176
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
788.28
-4.57
31.0
28.0
67.0
142.0
5.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0165821 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
4.35 μM
MBC
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
RECORD: Rec_0171347 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. enteritidis ATCC 13076
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
RECORD: Rec_0176714 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus ATCC 43400
1.11 μg/mL
MBC
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
RECORD: Rec_0190094 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa
PMID28335779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28335779/
RECORD: Rec_0190946 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
WI-38 (fibroblast) cells
Cytotoxicity
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
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