Peptide Database

Peptide NameEptotermin alfa

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length139 amino acids

Chemical FormulaC683H1061N197O208S10

DescriptionStandard

        STGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH
    

Molecular Weight15680.58 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)2.75

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0198

GRAVY Index-0.50

Hydrophobic Moment 0.59

Boman Index-0.06

Instability Index52.58

Aliphatic Index 67.41

Aromaticity 0.0935

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6577.41

LogP -74.25

H-bond Donors 231.0

H-bond Acceptors 225.0

Rotatable Bonds 512.0

Heavy Atoms 1098.0

Ring Count 26.0

Amide Bonds 157.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120650 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

RECORD: Rec_0323842 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide38-104; 67-136; 71-138

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Growth factor signaling Heparin-binding