Peptide Database

Peptide NameFilaggrin-2 (2321-2391)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC327H486N110O110

DescriptionStandard

        SSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLSWSTDSTANKQLSRH
    

Molecular Weight7718.03 Da

Isoelectric Point (pI)9.87

Net Charge (pH 7.0)4.07

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.0582

GRAVY Index-1.39

Hydrophobic Moment 0.43

Boman Index-0.25

Instability Index53.90

Aliphatic Index 25.14

Aromaticity 0.1000

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3587.03

LogP -55.79

H-bond Donors 131.0

H-bond Acceptors 121.0

Rotatable Bonds 251.0

Heavy Atoms 547.0

Ring Count 18.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0332186 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetPseudomonas aeruginosa ATCC 33354[MEC = 3.3 microM]

RECORD: Rec_0356205 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606