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MYP_013736
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Basic Information
Filaggrin-2 (2321-2391)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Standard
70 amino acids
C327H486N110O110
Standard
Sequence
SSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLSWSTDSTANKQLSRH
Physicochemical Analysis
7718.03 Da
9.87
4.07
3.50
0.0582
-1.39
0.43
-0.25
53.90
25.14
0.1000
16960.00
16960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3587.03
-55.79
131.0
121.0
251.0
547.0
18.0
75.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031938 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 6538[MEC >129.6 microM]
PMID26371476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26371476/
RECORD: Rec_0172016 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa ATCC 33354
3.3 μM
MIC
PaperSkin-Derived C-Terminal Filaggrin-2 Fragments Are Pseudomonas aeruginosa-Directed Antimicrobials Targeting Bacterial Replication
RECORD: Rec_0209012 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 11775[MEC = 13 microM]
PMID26371476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26371476/
RECORD: Rec_0220020 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 11775
13 μM
MIC
PaperSkin-Derived C-Terminal Filaggrin-2 Fragments Are Pseudomonas aeruginosa-Directed Antimicrobials Targeting Bacterial Replication
RECORD: Rec_0253971 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 24433[MEC >129.6 microM]
PMID26371476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26371476/
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