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MYP_013732
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Basic Information
Ranatuerin-1C
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C114H206N32O31S3
Standard
Sequence
SMLSVLKNLGKVGLGLVACKINKQC
Physicochemical Analysis
2617.25 Da
9.70
3.44
3.19
0.1375
0.64
0.57
0.18
26.11
132.40
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1035.53
-9.68
37.0
38.0
94.0
180.0
0.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0170350 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Ranatuerin
8404
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
19-25
Disulfide bridge: C19,C25
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
55 μM
MIC
PaperPeptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens. PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
RECORD: Rec_0258457 VERIFIED: NO
Provenance & Taxonomy
Rana clamitans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0286101 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Ranatuerin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
19-25
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
55 μM
MIC
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0291470 VERIFIED: YES
Provenance & Taxonomy
Lithobates clamitans [Animal]
Frog skin active peptide (FSAP); Ranatuerin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0328047 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Ranatuerin
8404
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
19-25
Disulfide bridge: C19,C25
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
58 μM
MIC
PaperPeptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens. PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
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