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MYP_013722
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Basic Information
Dermadistinctin-Q1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C135H231N37O37S
Standard
Sequence
ALWKNMLKGIGKLAGQAALGAVKTLVGAES
Physicochemical Analysis
2996.57 Da
10.00
2.79
2.60
0.0932
0.47
0.70
0.26
0.38
117.33
0.0333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1191.03
-10.31
41.0
41.0
104.0
210.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0132718 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Enterococcus faecalis
PMID10477123;18644413 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
RECORD: Rec_0167877 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
1.3 μM
MIC
PMID10477123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
RECORD: Rec_0191254 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus, Enterococcus faecalis and, Pseudomonas aeruginosa and, Escherichia coli
RECORD: Rec_0211201 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterococcus faecalis
22 μM
MIC
PaperAntimicrobial peptides from the Brazilian frog Phyllomedusa distincta.
RECORD: Rec_0217664 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PMID10477123;18644413 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
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