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MYP_013680
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Basic Information
Parabutoporin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
45 amino acids
C229H379N61O61S
Standard
Sequence
FKLGSFLKKAWKSKLAKKLRAKGKEMLKDYAKGLLEGGSEEVPGQ
Physicochemical Analysis
4994.90 Da
10.00
6.76
6.53
0.1502
-0.70
0.67
-0.14
19.43
76.00
0.0889
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2009.35
-15.15
70.0
69.0
182.0
352.0
6.0
45.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0176636 VERIFIED: YES
Provenance & Taxonomy
Parabuthus schlechteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
3.1 μM
MIC
PMID12354111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
RECORD: Rec_0179079 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0195549 VERIFIED: YES
Provenance & Taxonomy
Parabuthus schlechteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID12354111;12457879;14575699;15245865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
RECORD: Rec_0205546 VERIFIED: YES
Provenance & Taxonomy
Parabuthus schlechteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperAntibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.
RECORD: Rec_0222766 VERIFIED: YES
Provenance & Taxonomy
Parabuthus schlechteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
N. crassa
2.5 μM
MIC
PMID12354111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
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