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MYP_013560
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C32H47N9O6
Standard
Sequence
WLAHK
Physicochemical Analysis
653.77 Da
8.76
0.85
0.59
0.1693
-0.48
0.26
0.12
63.06
98.00
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
250.21
0.22
9.0
8.0
19.0
47.0
3.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0152480 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-Lactalbumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Osteoanabolic Bone-protective
Cell proliferation assay
PaperOsteoanabolic activity of whey-derived anti-oxidative (MHIRL and YVEEL) and angiotensin-converting enzyme inhibitory (YLLF, ALPMHIR, IPA and WLAHK) bioactive peptides | Pandey, M. et al. | DOI: 10.1016/j.peptides.2017.11.004 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
RECORD: Rec_0157507 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
176.4 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0173712 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-Lactalbumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic Lymphocyte-proliferative Immunomodulatory
Murine splenocytes
Cell proliferation assay
PaperProliferative effects of synthetic peptides from β-lactoglobulin and α-Lactalbumin on murine splenocytes | Jacquot, A. et al. | DOI: 10.1016/j.idairyj.2010.02.013 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
RECORD: Rec_0185805 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-Lactalbumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
77 μM
IC50
PaperAngiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides | Pihlanto-Leppala, A. et al. | DOI: 10.1017/s0022029999003982 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
RECORD: Rec_0186180 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
77 μM
IC50
PaperAngiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. PMID10717843 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10717843/
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