Peptide Database

Peptide NameRNase 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length128 amino acids

Chemical FormulaC610H966N192O198S13

DescriptionStandard

        KESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST
    

Molecular Weight14574.21 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)6.13

Net Charge (pH 7.4) 5.52

Charge Density (pH 7.0) 0.0479

GRAVY Index-0.92

Hydrophobic Moment 0.63

Boman Index-0.24

Instability Index63.90

Aliphatic Index 41.02

Aromaticity 0.0703

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6391.76

LogP -86.35

H-bond Donors 230.0

H-bond Acceptors 222.0

Rotatable Bonds 484.0

Heavy Atoms 1013.0

Ring Count 21.0

Amide Bonds 143.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0244732 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsAPD analysis reveals this sequence is most similar (25%) to mouse RNase 6. Residue 88 Asn is glycosylated

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetEscherichia coli strains, Candida albicans