Peptide Database

Peptide NameBradykinin-potentiating peptide 3

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Membrane / Ion-channel modulation ▸ Ion channel modulation

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC61H83N17O15

DescriptionStandard

        QEWPPGHHIPP
    

Molecular Weight1294.42 Da

Isoelectric Point (pI)5.98

Net Charge (pH 7.0)-1.06

Net Charge (pH 7.4) -1.37

Charge Density (pH 7.0) -0.0966

GRAVY Index-1.51

Hydrophobic Moment 0.18

Boman Index0.07

Instability Index85.28

Aliphatic Index 35.45

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 472.70

LogP -2.27

H-bond Donors 13.0

H-bond Acceptors 16.0

Rotatable Bonds 31.0

Heavy Atoms 93.0

Ring Count 8.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004544 VERIFIED: YES

Provenance & Taxonomy

OrganismLachesis muta muta [Animal]

FamilyBradykinin-potentiating peptide

Tax ID8753

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Enzyme modulation Ion channel modulation ACE inhibitory

Targetangiotensin-converting enzyme

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0015436 VERIFIED: YES