Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length562 amino acids

Chemical FormulaC2694H4251N801O836S25

DescriptionStandard

        MGYREDCYGRGLALNGDKTTTGASCISSTGSRVSYFGRGIVRVGDVTTDCPKCGRYGRIIDGESRSQYFGAAAAVDGSLVVCHCPEGSNRVIAPAGEWLGRGKSPEQQAEERQKVRLATRKAEQAAQEKRLAAERERNRVFAKSCLRGEGCNDAGDQCEPHSNFARMAFYQAAPVTDTTARQHTESGKKQPSAEAIPKPKRHSALYKWRYGNHEEMDYQAALATMAGMARVQTAMAGANVLTPIAGNLAVPGTWAVSAARIAVGGIGAPLAGLLVGMMPGRLNNGEQDFIDRMRLEQMREAPTRVRFTWENDTQGNPVPHGWHTPAGQDKVRVRSMQWNNSRQAYTFTTEEDDPLTLIWTPDSSGMEIPAHTGDQSPPQLPGSVMVDPLPDNNGFDSTVSPAPEEKGFADYILILPLPNIPPIYIYLSKPPVEFLEVELYSDFIRRSRQGKYEADHMPSRAAVERYYMNKYPTMDIEQITELSNRVASIVIPKEVHRRVSETFGGRNSDTRIDLDSRDLRAAADSNLDAIKPKLQEYGATEQQIEAVRARVHELNSKIGLYK
    

Molecular Weight62038.06 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.53

Net Charge (pH 7.4) -1.58

Charge Density (pH 7.0) -0.0009

GRAVY Index-0.58

Hydrophobic Moment 0.77

Boman Index-0.09

Instability Index44.45

Aliphatic Index 68.29

Aromaticity 0.0712

Extinction Coeff. Reduced 68300.00

Extinction Coeff. Oxidized 68800.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263148 VERIFIED: YES

Provenance & Taxonomy

OrganismRouxiella aceris [Bacterium]

FamilyPyocin/Colicin

Tax ID2703884

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli