Peptide Database

Peptide NameNeuropeptide K

Function Ontology

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling

Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity

Neurological / Signaling ▸ Tachykinin peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC175H283N51O53S

DescriptionStandard

        DADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLM
    

Molecular Weight3981.49 Da

Isoelectric Point (pI)8.40

Net Charge (pH 7.0)1.02

Net Charge (pH 7.4) 0.66

Charge Density (pH 7.0) 0.0284

GRAVY Index-0.40

Hydrophobic Moment 0.36

Boman Index-0.03

Instability Index57.70

Aliphatic Index 89.44

Aromaticity 0.0556

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1690.60

LogP -17.30

H-bond Donors 59.0

H-bond Acceptors 58.0

Rotatable Bonds 138.0

Heavy Atoms 280.0

Ring Count 5.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0308288 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyNeuropeptide K

Tax ID10036

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Vasoactive Vasodilator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0315313 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]; Homo sapiens [Animal]; Mesocricetus auratus [Animal]; Rattus norvegicus [Animal]

Tax ID9823, 9606, 10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0358571 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyTachykinin

Tax ID10036

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Tachykinin Neuropeptide Neuromodulator

RECORD: Rec_0365427 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 88.9%, E 0.0%, T 5.6%, C 5.6% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

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