Peptide Database

Peptide NameHR 1-36 / HRNR 2663-2690

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC119H185N47O43

DescriptionStandard

        LGHSSSHGQHGSGSGRSSSRGPYESRLGH
    

Molecular Weight2962.03 Da

Isoelectric Point (pI)10.74

Net Charge (pH 7.0)2.11

Net Charge (pH 7.4) 1.70

Charge Density (pH 7.0) 0.0728

GRAVY Index-1.33

Hydrophobic Moment 0.49

Boman Index-0.23

Instability Index58.62

Aliphatic Index 26.90

Aromaticity 0.0345

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1452.44

LogP -26.35

H-bond Donors 54.0

H-bond Acceptors 49.0

Rotatable Bonds 97.0

Heavy Atoms 209.0

Ring Count 6.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273240 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa ATCC 10145

Activity0.15 μg/mL

MethodLD90 (P. aeruginosa-cidal assay)

PaperCationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives PMID30833614 Evidence URLhttps://patents.google.com/patent/US20200115426A1/en PatentUS 2020/0115426 A1

RECORD: Rec_0432046 VERIFIED: YES