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MYP_013379
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Basic Information
AVP-p
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C98H170N26O27
Standard
Sequence
LNLFKKTINGLISDSLVIR
Physicochemical Analysis
2144.56 Da
9.99
1.76
1.55
0.0926
0.54
0.60
0.14
3.79
158.95
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
885.23
-6.91
31.0
29.0
75.0
151.0
1.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0049288 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 24850726 PMID24850726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24850726/
RECORD: Rec_0081491 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 24850726 PMID24850726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24850726/
RECORD: Rec_0204993 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
Vero cells or human foreskin fibroblasts (HFF) up to 100 μM
100 μM
Cytotoxicity
PaperPubMed PMID: 24850726 PMID24850726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24850726/
RECORD: Rec_0252038 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Noen
Bio-Activity Profile
Antiviral Fusion inhibition
Pichinde virus (PICV) | Vero cells
7.05±2.19 μM
IC50
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperInhibition of arenavirus infection by a glycoprotein-derived peptide with a novel mechanism. | Spence JS, Melnik LI, Badani H, Wimley WC, Garry RF. | J Virol. 2014 Aug;88(15):8556-64. | DOI:10.1128/JVI.01133-14 | PMID:24850726 PMID24850726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24850726/
RECORD: Rec_0257863 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Pichinde virus (PICV):inhibition of viral infection in Vero cells
7.05±2.19 μM
IC50
PaperPubMed PMID: 24850726 PMID24850726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24850726/