Peptide Database

Peptide NameCentrocin 1 (EeCentrocin 1) [Cleaved into: Centrocin 1; heavy chain; Centrocin 1; light chain]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length119 amino acids

Chemical FormulaC570H919N159O174S8

DescriptionStandard

        MMIKIAVVLCAVMATTMVRAKYVEEQELADLLDLLISEEVSSPDDAVALQGWWRRTVDKVRNAGRKVAGFASKACGALGHSPQEARAKVLEAFPEMKEADLDEEDIGKYCGYAHALNGR
    

Molecular Weight13039.88 Da

Isoelectric Point (pI)5.18

Net Charge (pH 7.0)-4.33

Net Charge (pH 7.4) -4.73

Charge Density (pH 7.0) -0.0364

GRAVY Index-0.10

Hydrophobic Moment 0.77

Boman Index0.02

Instability Index44.31

Aliphatic Index 91.09

Aromaticity 0.0588

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5347.83

LogP -48.46

H-bond Donors 188.0

H-bond Acceptors 180.0

Rotatable Bonds 441.0

Heavy Atoms 911.0

Ring Count 14.0

Amide Bonds 123.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009410 VERIFIED: YES

Provenance & Taxonomy

OrganismEchinus esculentus [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria